Just two years ago in 2018, DANE carried out the National Population and Housing Census which estimated the five dimensions and 15 indicators of Colombia’s MPI. This analysis is now being cross-checked and used as a critical tool for crafting and targeting the government’s response to COVID-19. In a country where informal work accounts for 45% of the population in urban areas and more than 60% in rural areas, there is a pressing need to target those who need it most in the midst of the pandemic.